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Spironolactone is contraindicated in Aldactone patients with moderate to severe renal impairment. Related Drugs. Things you must not do Do not take potassium supplements or use salt substitutes that contain potassium. Ainsworth 10 November Aronson 2 March This depends on your condition and whether or not you are Aldactne any other medicines. Tell all doctors, dentists and pharmacists who are treating you that Adlactone are taking Aldactone. In a randomized evaluation which studied people with severe congestive heart failurepeople treated with spironolactone were found to have a relative risk of death Aldactnoe 0. Eye care: Dr Joe Kosterich. Explore Apps. Polonsky; P. Tell your Alactone or pharmacist as soon as possible if you do not feel Aldactonr while you are taking Aldactone. Clinical Pharmacology and Therapeutics of Hypertension. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. There is limited paediatric data available see sections 5. Warrell; Edward J. Spironolactone is rapidly and extensively metabolized in the liver upon oral administration and has a very short terminal half-life of 1. Brittain 26 November Keep your tablets in their original packaging, including outer carton, until it is time to take them. Medicine Name Arthrotec Recommend this article. If you take too much overdose Immediately telephone your doctor or Poisons Information Centre telephone 13 11 26 or go to Accident and Emergency at your nearest hospital if you think that you or anyone else may have taken too much Aldactone. Your doctor may do blood tests to check your sodium and potassium levels and see how your kidneys are working. Aldactone isn't a first-line treatment for acne, so your dermatologist will likely have you try the conventional acne medications first: topical retinoidstopical antibioticsbenzoyl peroxide or a combination of these medications. Due to its antiandrogenic properties, spironolactone can cause effects associated with low androgen levels and hypogonadism in males. Given that the compelling evidence of the role of aldosterone in the pathophysiology of cardiovascular disease extends beyond ion transport, this classification is presently obsolete. Azelaic acid Benzoyl peroxide 8-Hydroxyquinoline Blue light therapy Tea tree oil. Medicine Name Aldactone mg film coated tablets. This can lead to various endocrine side effects that can limit the use of spironolactone. It isn't always effective when used on its own, but works well when used in conjunction with conventional acne treatment medications. Spironolactone 25 mg-MYL, white, round, film coated. Tell your doctor if you become pregnant while you are taking Aldactone. Starting dose: mg daily. D 2 receptor antagonists prolactin releasers e. In some cases, drinking too much Aldactone can be as unsafe as not drinking enough. Retrieved 29 November Steroidal Activity in Experimental Animals and Man. If you are being treated for high blood pressure, keep using this medication even if you feel well. Dried fruit, bananas and oranges are some foods that contain high amounts of potassium. Firth For these reasons, before you start taking spironolactone it is important that your doctor or pharmacist knows:. For details see our conditions. It is not known whether Aldactone will harm an unborn baby. About About Drugs. This is not a complete list of side Alxactone and others may occur. Oxford University Press. Trending Articles. Spironolactone is contraindicated in paediatric patients with moderate to severe renal impairment. Keep all appointments with your doctor and the laboratory. It tends to work best as an additional acne treatment, rather than the sole treatment.
(Active Ingredient: Spironolactone)
Aldactone is used for treating swelling and fluid retention in patients with congestive heart failure, liver cirrhosis, or kidney problems (nephrotic syndrome). It is also used for treatment of high blood pressure.
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    Aldactone is used for treating swelling and fluid retention in patients with congestive heart failure, liver cirrhosis, or kidney problems (nephrotic syndrome). It is also used for treatment of high blood pressure. It may also be used to treat or prevent low blood potassium. It may also be used to treat excess secretion of the hormone aldosterone by the adrenal gland. Aldactone is a potassium-sparing diuretic. It works by blocking the hormone aldosterone, causing the kidney to eliminate excess water, save potassium, and lower blood pressure.


    Use Aldactone as directed by your doctor.

    • Take Aldactone by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
    • Aldactone may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
    • If you miss a dose of Aldactone, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If more than one dose is missed, restart the medication and advise your doctor or pharmacist at your next appointment.

    Ask your health care provider any questions you may have about how to use Aldactone.


    Store Aldactone at room temperature, between 59 and 77 degrees F (15 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Aldactone out of the reach of children and away from pets.


    Active Ingredient: Spironolactone.

  • Do NOT use Aldactone if:

    • you are allergic to any ingredient in Aldactone
    • you are unable to urinate, have severe kidney problems, or have high blood potassium levels
    • you are taking a potassium supplement, another potassium-sparing diuretic (eg, amiloride, triamterene), or another aldosterone-blocker (eg, eplerenone).

    Contact your doctor or health care provider right away if any of these apply to you.

    Some medical conditions may interact with Aldactone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, planning to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances
    • if you have high acidity in your body fluids; low blood sodium levels; high blood potassium levels; kidney, liver, or heart disease; diabetes; or high urea or nitrogen in your blood
    • if you have menstrual disease.

    Some medicines may interact with Aldactone. Tell your health care provider if you are taking any other medicines, especially any of the following:

    • Adrenocorticotropic hormone (corticotropin) (ACTH) or corticosteroids (eg, prednisone) or because low blood electrolyte levels may occur
    • Barbiturates (eg, phenobarbital) or narcotics (eg, morphine) because dizziness upon standing may occur
    • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg, valsartan), cyclosporine, macrolide immunosuppressives (eg, tacrolimus), other aldosterone-blockers (eg, eplerenone), other potassium sparing diuretics (eg, amiloride, triamterene), or potassium supplements because high blood potassium levels may occur (eg, listlessness, confusion, abnormal skin sensations of the arms and legs, heaviness of limbs, slowed heart rate, irregular heart rhythm, potentially life-threatening slow or irregular heartbeat)
    • Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease Aldactone's effectiveness and increase the risk of kidney problems and high blood potassium
    • Digoxin, digitoxin, lithium, nondepolarizing muscle relaxants (eg, tubocurarine), or quinidine because the risk of their side effects and toxicity may be increased by Aldactone
    • Pressor amines (eg, norepinephrine) because their effectiveness may be decreased by Aldactone.

    This may not be a complete list of all interactions that may occur. Ask your health care provider if Aldactone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    Important safety information:

    • Aldactone may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Aldactone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
    • Aldactone can raise your body's potassium levels. This is more likely to occur in people with kidney problems or diabetes, in the elderly, or if the patient is severely ill. Potassium levels must be closely monitored in people with any of these problems or illnesses. If not treated, high potassium levels can be fatal.
    • Check with your doctor before you use a salt substitute or a product that has potassium in it.
    • Lab tests, including kidney function, blood pressure, blood potassium, and chemistries, may be performed while you use Aldactone. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
    • Use Aldactone with caution in the elderly; they may be more sensitive to its effects.
    • Aldactone should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
    • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Aldactone while you are pregnant. Aldactone is found in breast milk. Do not breast-feed while taking Aldactone.
  • All medicines may cause side effects, but many people have no, or minor, side effects.

    Check with your doctor if any of these most common side effects persist or become bothersome:

    Diarrhea; drowsiness; headache; nausea; stomach cramping; vomiting.

    Seek medical attention right away if any of these severe side effects occur:

    Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; change in the amount of urine produced; confusion; dark urine; decreased sexual ability; enlarged breasts in men; irregular or missed menstrual periods; pale stools; severe or persistent stomach pain; symptoms of abnormal fluid or electrolyte levels (eg, fast, slow, or irregular heartbeat; increased thirst; muscle weakness; severe or persistent dry mouth, nausea, or vomiting; severe or persistent dizziness or drowsiness; unusual fatigue or sluggishness; tingling sensation); yellowing of the skin or eyes.

    This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.